How CBD, CBG and the ECS Can Help Balance Mood

The endocannabinoid system
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Mood swings are a common symptom of hormonal changes and imbalances with premenstrual syndrome (PMS), menopause and perimenopause. Fortunately, it is now common knowledge that both Cannabidiol (CBD) and Cannabigerol (CBG) through our very own endocannabinoid system (ECS) can help balance things out.

The ECS is responsible for maintaining homeostasis in the body. Cannabinoid receptors like CB₁ and CB₂ play a key role in mood regulation. Combined with the potential benefits of CBD and CBG, this makes for a powerful mood swing-relief duo.

This article will explore how the ECS works and how CBD combined with CBG can help balance mood swings and irritability in women.

What is the Endocannabinoid System?

The endocannabinoid system (ECS) is a system that lives in all animals, and is responsible for regulating almost all important aspects of our biochemistry (mood/stress/pain/appetite/gut health/tiredness/brain functions – you name it). When we experience mood swings, pain, inflammation, anxiety, or any other PMS or menopausal symptom, the ECS is put to work by bringing our bodies back into balance.

One way the ECS does this is by producing endocannabinoids – these are molecules naturally produced by our bodies that bind to cannabinoid receptors and help  regulate these dysfunctions.

What are Cannabinoid Receptors?

Cannabinoid receptors are a sort of communication centres found throughout the body that endocannabinoids (and cannabinoids like CBD and CBG) “speak” and connect with. There are two kinds of cannabinoid receptors, CB₁ and CB₂.

CB₁ receptors are found mainly in the central nervous system (CNS), including the brain. They are responsible for regulating mood and other hormone-related symptoms.

CB₂ receptors are in the peripheral immune system, including the nerves outside the brain and spinal cord. These receptors are tasked with regulating inflammation and immune cell functions.

CBD:CBG for mood

How Cannabinoids May Help

Cannabidiol (CBD) is a phytocannabinoid. This means it comes from a plant however has a very similar structure to the endocannabinoids (the ones produced naturally by our bodies). Therefore, may be useful for helping modulate both CB₁ and CB₂ receptors, making it a powerful symptom-relief tool in regulating mood. It is also a known anxiolytic, meaning it has anti-anxiety properties. This can also be helpful for people experiencing anxiety or depression due to their hormonal or perimenopause symptoms.

CBD is also a possible anti-inflammatory agent. This is important for menopause symptom relief, as many menopausal symptoms are caused or exacerbated by inflammation. In addition, symptoms like inflammation can further cause discomfort, affecting our mood.

Cannabigerol (CBG), another phytocannabinoid, similarly to CBD also may communicate with our endocannabinoid system. CBG on the other hand however actually binds to our cannabinoid receptors (CB₁ and CB₂) seemingly making it more effective than its cannabinoid cousin CBD. CBG is currently being used for helping cope with chronic pain, severe anxiety, insomnia and depression. In a survey done on the medical use of CBG, users reported greater efficacy of CBG-predominant cannabis over conventional pharmacotherapy. CBG is also known for being a powerful anti-inflammatory agent, antibacterial and a neuroprotector.

When combined, CBD and CBG become to powerful ingredients that work in synergy to help alleviate and manage most negative symptoms that come hand-in-hand with peri/menopause.

How to Use CBD:CBG for Mood Swings

There are a few different ways to use CBD:CBG for menopause symptom relief.

You can take CBD:CBG orally in the form of tinctures, capsules, or gummies. In addition, for menopausal women or women experiencing chronic pain, CBD:CBG can be taken in the form of topical cream or balm and applied directly to the affected area.

It seems however, that the most effective way to intake CBD:CBG is via a sublingual tincture. This is due to the fact that when taken under the tongue, the effects are better absorbed by the body and felt quicker.

It is best to start with a low dose and increase as needed when first starting out. It is also important to consult with a healthcare professional before starting any mood symptom-relief regimen to help you establish the best course of action for your individual needs.

See our recommended CBD:CBG tincture here.


CBD:CBG is a safe and effective PMS, menopause and perimenopause symptom relief option for womem. If you are experiencing menopause or hormonal-related symptoms like mood swings, anxiety, depression, or chronic pain, CBD:CBG may be able to help you find some alleviation.

Our CBD tincture combines a unique CBG combination (along with other ingredients) to help alleviate menopausal symptoms. It has been scientifically developed for women by women with your menstrual and hormonal concerns in mind.

illumis PMS formula


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